4 Effect of SFRP-1 on osteoclastogenesis in rat bone marrow cell cultures. protein-1 (SFRP-1), which was found to be down-regulated at days Oligomycin 3 and 9. Using rat bone marrow cultures to conduct in vitro osteoclastogenic assays, it was demonstrated that SFRP-1 inhibited osteoclast formation in a concentration-dependent fashion. However, with increasing concentrations of SFRP-1,…

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In agreement with this magic size, retroviral expression of present in over 50% of T-ALL patients at diagnosis 21 has brought enormous interest for the development of molecularly personalized therapies in T-ALL and prompted the initiation of a clinical trial to test the effectiveness of blocking NOTCH1 signaling with a small molecule GSI with this…

Read More “In agreement with this magic size, retroviral expression of present in over 50% of T-ALL patients at diagnosis 21 has brought enormous interest for the development of molecularly personalized therapies in T-ALL and prompted the initiation of a clinical trial to test the effectiveness of blocking NOTCH1 signaling with a small molecule GSI with this disease” »