Becker B
Becker B., Multhoff G., Farkas B., Wild P. of HSP90 without affecting Ca2+ oscillations observed with EGF. Extracellular HSP90 induced EGFR phosphorylation at Tyr-1068, and this event was prevented by both the protein kinase C inhibitor, rottlerin, and the c-Src inhibitor, PP2. Altogether, our results suggest that extracellular HSP90 transactivates EGFR/ErbB1 through TLR4 and a…