While among our initial research demonstrated that splenic atrophy in experimental stroke is accompanied by increased FoxP3+ regulatory T-cells (Offner et al
While among our initial research demonstrated that splenic atrophy in experimental stroke is accompanied by increased FoxP3+ regulatory T-cells (Offner et al., 2006b), our latest research using conditional Treg-deficient mice didn’t implicate Compact disc4+Compact disc25+FoxP3+Tregs as having defensive activity against MCAO (Ren et al., 2011). supply the first proof both immunoregulatory and defensive features of…