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Discovery and Biological Characterization of Potent MEK inhibitors in melanoma

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Weekes CD, Song D, Arcaroli J, Wilson LA, Rubio-Viqueira B, Cusatis G, Garrett-Mayer E, Messersmith WA, Winn RA, Hidalgo M

Posted on August 1, 2022 By scienzaunder18

Weekes CD, Song D, Arcaroli J, Wilson LA, Rubio-Viqueira B, Cusatis G, Garrett-Mayer E, Messersmith WA, Winn RA, Hidalgo M. proteins. Furthermore SELN6.0 decreased the amount of NICD, which consecutively decreased the expression of Hes-1, its nuclear target. Although SELN affected the survival of human pancreatic cancer SOJ-6 cells the Notch pathway inhibition, the MiaPaCa-2…

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