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Discovery and Biological Characterization of Potent MEK inhibitors in melanoma

MEK inhibitor

K

Posted on April 24, 2022 By scienzaunder18

K., Coffin J. lysate phosphorylation on individual proteins arrays (18). Typically, isotope-labeling continues to be the primary technique used to recognize a customized substrate, but this is complicated when coping with a high-content array specifically, like the individual proteome arrays (HuProt array), due to the high thickness of published (100 m of center-to-center length). UMB24…

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IGF Receptors

Aggregation of -synuclein and its presence as the dominant protein in Lewy bodies (LB) is a hallmark of a group of neurodegenerative diseases classified as the synucleinopathies

Posted on March 2, 2022 By scienzaunder18

Aggregation of -synuclein and its presence as the dominant protein in Lewy bodies (LB) is a hallmark of a group of neurodegenerative diseases classified as the synucleinopathies. in their assembly and stability dependent on the phosphorylation state of the protein. In disease-affected neurons, hyperphosphorylation leads to the accumulation of the tau protein into aggregates, mainly…

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IGF Receptors

Chia et al

Posted on February 27, 2022 By scienzaunder18

Chia et al.58 transduced autologous dendritic cells with an adenovirus vector expressing a truncated type of LMP1 and full length LMP2; shot of 16 sufferers with metastatic nasopharyngeal carcinoma using the dendritic cells led to a UR 1102 incomplete response in a single patient and steady disease in two sufferers, although no enlargement of LMP1…

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IGF Receptors

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