Among the signaling paradigms regarded as employed by estrogens are those involving G protein, while demonstrated in vascular cells [16-18] and neurons [19]
Among the signaling paradigms regarded as employed by estrogens are those involving G protein, while demonstrated in vascular cells [16-18] and neurons [19]. Using antibodies against the GTP-bound type of G proteins subtypes s and i, we demonstrated that xenoestrogens (bisphenol A, nonylphenol) triggered Gi at 15-30 sec; all alkylphenols examined suppressed activation by 5…